Located on the Main River between Nuremberg and Frankfurt, Wurzburg was devastated by bombs and firestorms during World War II. Its major historic monuments have been restored, but since 90 percent of it was destroyed during the war, much of the city is distinctly modern, with a bit less charm than other Bavarian towns.
Wurzburg is home to Germany's second-oldest university, and about a quarter of its 130,000 residents are students. That academic atmosphere has produced 13 Nobel Prize winners.
The city was once ruled by prince-bishops, who held both religious and political power. The main attraction is their Residenz palace, built in the late 18th century. Some river cruise lines offer an included or optional excursion to the nearby town of Rothenberg from the port.