(2:40 p.m. EST) -- Oceania's recently refurbished Insignia will set the stage for the luxury line's 2021 world cruise, which includes 100 ports of call in 44 countries, opportunities to visit 125 UNESCO World Heritage Sites, and several overnight stays -- all in 180 days.

The ship will depart from Miami on January 9, 2021, and end its 39,000-nautical-mile journey in New York on July 9, 2021. A 164-day itinerary, leaving Los Angeles on January 25, 2021 and ending in New York in July, also is available.

Additional highlights of the cruise include three day-stops in Myanmar and Turkey and one- or two-night stays in destinations such as Bora Bora, Cairns, Hong Kong, Saigon, Bangkok, Singapore, Mumbai, Dubai, Luxor, Jerusalem, Venice, Lisbon, Seville and Bordeaux.

Five special shoreside events are scheduled for: Hilo, Hawaii (traditional performances at the Umauma Falls Nature Center); Brisbane, Australia (Spirits of the Red Sand aboriginal dinner experience); Istanbul, Turkey (an evening at the Binbirdirek Cistern); Dublin, Ireland (Riverdance performance at the Mansion House); and Livorno, Italy (Alpemare Beach Resort, which is owned by world-renowned Italian singer and songwriter Andrea Bocelli and his family). The Alpemare Beach Resort stop will include an exclusive performance by Andrea Bocelli's son, Matteo.

Passengers may also opt for additional overland excursions ranging from one to three nights, including a tour of Nepal, Angkor Wat, the Taj Mahal, and Luxor and the pyramids.

Bob Binder, President and CEO of Oceania Cruises, cited Rudyard Kipling's 1873 novel "Around the World in 80 Days," which details one man's determination to circumnavigate the globe -- and win a bet with friends -- in 80 days via steamer ship and rail.

"This world cruise is particularly exciting [with] six continents, three oceans and 44 countries," he said. "It's an itinerary designed to appeal to the Kipling in all of us, matching our famous onboard luxury with personal and profound visits to the world's most compelling destinations."

Oceania's 2020 world cruise will be the line's first spanning 180 days; it will visit 95 ports across four continents and include 17 overnights.

Fares for the 2021 world cruise start at $38,499 per person, not including airfare, for an inside based on double occupancy. Value-added packages that include airfare, prepaid gratuities, internet and other perks also are available for booking.