We booked this trip realizing that many people were staying away, but believing based on what we had read, that Egypt is safe. And it was. The people are lovely, the level of security is high. So if you've always wanted to see Karnak, the Valley of the Kings and the Pyramids, go now while tourism is dead. We went in late October, but I wish we'd gone a bit later--it was quite hot in the south. So do think about climate, and weigh that against the possibility of tourist crowds. In 2016 the crowding issue should not be a problem.
Airport pickups and drop-offs were all done very nicely--this was especially appreciated when we arrived in Cairo, since we were not part of a group. Our agent was waiting for us before we even went through security. We got our visas with no problem and he shepherded us through immigration and got us into a minibus for the long ride to Cairo. All other flights during the tour were accompanied by our tour guide.
As well as our 7 nights on Tosca, we had two and two nights at the Cairo Four Seasons. A superb hotel, overlooking the Nile. Wonderful experience. We also had tours there, including the Cairo Museum, the Alabaster Mosque, the Pyramids (twice, once at night) and Saqqara.
Great cabin, although we were rafted on our side most of the time, so if you want a better view of the river, perhaps try the other side. But this may be completely arbitrary. We liked being on deck 2, since it was two flights up to the sundeck, one flight down to the lobby, and another flight down to the dining room. We were forward, not sure how aft would be.