I would rate Venice among the top five ports to sail in or out of. Spectacular! I personally love Venice, but it is totally handicap-unfriendly as almost all the 400+ bridges are upstairs and downstairs so not easy to navigate with luggage or push strollers. Other reviewers have already described the challenging port, so I shall forbear.
We loved the cruise (very port-intensive); the ports were all interesting; the food was very good; service was excellent; our cabin was spacious and kept spotless by Lavonie.
We loved the ship, lots of natural light from huge windows, BUT....
Large window, lots of natural light. Close to elevators. Very quiet, unlike cabins closer to Centrum which were very noisy from performances in the Centrum). Suitcases (one airplane carry-on, 1 medium-size) did not fit underneath beds so cluttered up closet. No fridge. Need to use credit card for safe.