Panama Canal & Central America Cruises

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Seabourn Encore
Seabourn Encore
Seabourn Encore Cabins
Seabourn Encore
Seabourn Encore Dining
Seabourn Encore
Seabourn Encore Activity/Entertainment
Seabourn Encore
Seabourn Encore
Seabourn Encore

19 Nights

19 Nights  Panama Canal & Central AmericaPanama Canal Cruise

Port: Los Angeles • Puerto Vallarta • Huatulco • Puerto Chiapas • Puerto Quetzal • Puntarenas • +5 more

153
Apr 9, 2025
Seabourn Cruise Line
Zaandam Cabins
Zaandam
Zaandam Dining
Zaandam
Zaandam Activity/Entertainment
Zaandam
Zaandam
Zaandam

15 Nights

15 Nights  Panama Canal & Central AmericaPanama Canal Cruise

Port: Miami • Half Moon Cay • Cartagena • Panama Canal • Panama Canal • Puntarenas • +4 more

580
Mar 7, 2025
Holland America Line
Norwegian Jade
Norwegian Jade
Garden Cafe on Norwegian Jade
Norwegian Jade
Norwegian Jade Activity/Entertainment
Norwegian Jade
Norwegian Jade Cabin
Norwegian Jade

11 Nights

11 Nights  Panama Canal & Central AmericaRepo - Panama Canal

Port: Panama City • Panama Canal • Cartagena • Aruba • Curacao • St. Kitts • Tortola • Puerto Plata • +1 more

2,095
Feb 9, 2025
Norwegian Cruise Line
Holland America Line's Rotterdam at Half Moon Cay, Bahamas. (Photo: Aaron Saunders)
Holland America Rotterdam
Rudi's Sel de Mer aboard Holland America Line's Rotterdam (Photo: Aaron Saunders)
Holland America Rotterdam
Passengers can use the Thermal Suite's Hydrotherapy Pool, part of the Greenhouse Spa, for an extra charge. (Photo: Aaron Saunders)
Holland America Rotterdam
Category VA Veranda stateroom aboard Rotterdam. (Photo: Aaron Saunders)
Holland America Rotterdam
Rotterdam's atrium is anchored by "Harps", a 7.5-ton sculpture valued at over $600,000. (Photo: Aaron Saunders)
Holland America Rotterdam

12 Nights

12 Nights  Panama Canal & Central AmericaPanama Canal Cruise

Port: Fort Lauderdale • Half Moon Cay • Aruba • Cartagena • Panama Canal • Gatun Lake • Colon • +3 more

144
Mar 16, 2025
Holland America Line
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MSC Cruises

Cruise Critic Favorite

16 Nights

16 Nights  Panama Canal & Central AmericaTranscanal Cruise

Port: Los Angeles • Puerto Vallarta • Huatulco • Puerto Chiapas • Puntarenas • Fuerte Amador • +3 more

1,041
Princess Cruises
Cruise Critic Favorite

16 Nights

16 Nights  Panama Canal & Central AmericaTranscanal Cruise

Port: Los Angeles • Puerto Vallarta • Huatulco • San Juan del Sur • Puntarenas • Fuerte Amador • +3 more

1,041
Oct 28, 2025
Princess Cruises

16 Nights

16 Nights  Panama Canal & Central AmericaTranscanal Cruise

Port: San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas • Puntarenas • Fuerte Amador • +3 more

1,250
Jan 29, 2027
Princess Cruises

28 Nights

28 Nights  Panama Canal & Central AmericaPanama Canal Cruise

Port: Vancouver • Santa Barbara • San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas • +12 more

1,226
Oct 5, 2025
Holland America Line

17 Nights

17 Nights  Panama Canal & Central AmericaPanama Canal Cruise

Port: San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas • Puerto Quetzal • Puntarenas • +5 more

915
Nov 1, 2025
Holland America Line

12 Nights

12 Nights  Panama Canal & Central AmericaTranscanal Cruise

Port: Fort Lauderdale • Bonaire • Curacao • Cartagena • Panama Canal • Colon • Puerto Limon • +2 more

1,911
Feb 28, 2025
Princess Cruises

16 Nights

16 Nights  Panama Canal & Central AmericaTranscanal Cruise

Port: Fort Lauderdale • Cartagena • Panama Canal • Fuerte Amador • Puntarenas • Puerto Quetzal • +2 more

2,013
Oct 7, 2026
Princess Cruises

10 Nights

10 Nights  Panama Canal & Central AmericaPanama Canal Cruise

Port: Panama City • Panama Canal • Cartagena • Curacao • Aruba • Montego Bay • Grand Cayman • +1 more

253
Apr 4, 2026
Oceania Cruises

16 Nights

16 Nights  Panama Canal & Central AmericaTranscanal Cruise

Port: Los Angeles • Puerto Vallarta • Huatulco • San Juan del Sur • Puntarenas • Fuerte Amador • +3 more

2,819
Sep 30, 2025
Princess Cruises

19 Nights

19 Nights  Panama Canal & Central AmericaPanama Canal Cruise

Port: Los Angeles • Puerto Vallarta • Huatulco • Puerto Chiapas • Puerto Quetzal • Puntarenas • +5 more

173
Apr 7, 2026
Seabourn Cruise Line

11 Nights

11 Nights  Panama Canal & Central America11 Nt Panama Canal & Perfect Day Holiday

Port: Fort Lauderdale • Cartagena • Panama Canal • Colon • Aruba • Curacao • +2 more

78
Dec 22, 2025
Celebrity Cruises

16 Nights

16 Nights  Panama Canal & Central AmericaTranscanal Cruise

Port: Fort Lauderdale • Aruba • Panama Canal • Fuerte Amador • Puntarenas • Puerto Chiapas • +3 more

2,266
Apr 4, 2027
Princess Cruises

More about the Panama Canal & Central America

What is the best time to cruise to the Panama Canal & Central America?

Panama Canal and Central America cruise season is from October through April. The rainy season doesn't end until November, so cruises here are more popular from December onward. For more: Best Month to Cruise to the Panama Canal

Which cruise lines go to the Panama Canal & Central America?

Most major cruise lines, including Princess and Holland America, feature at least a few Panama Canal sailings in addition to expedition lines like Tauck and Lindblad. Cruisers can choose from a partial or full transit of the canal (Panama Canal: Partial Transit vs. Full Transit). Cruises that specifically explore countries like Costa Rica (without the canal) are on offer, from small-ship lines like Windstar Cruises.

What are some things to do in the Panama Canal & Central America?

In addition to either a full or partial crossing of the Panama Canal, most cruises in this region include stops in popular ports throughout Central America, Mexico and the Caribbean. That means you can do anything from lounge on the beach to explore ancient ruins or enjoy some duty-free shopping. If you can, trek Arenal Volcano from Puerto Limon, Costa Rica.

Do you need a passport to take a cruise to the Panama Canal & Central America?

Yes, a passport is required for travel throughout Central America, including Panama.

What should I pack for a cruise to the Panama Canal & Central America?

The weather in this region tends to be hot and humid, so pack plenty of shorts and t-shirts. Since Panama Canal crossings tend to be longer sailings, be prepared that your cruise might have more than one formal night.

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