From the East: Take State Highway 87 West to Galveston Island. Use the Port Bolivar vehicle ferry system. Exit the ferry onto Ferry Rd./Highway 87. Turn right onto Harborside Dr. Continue approximately 20 city blocks. Turn right onto Kempner/22nd St. and continue to the cruise terminals.
From the North and the West: Take Interstate 45 South to Galveston Island. Take Exit 1C. Follow the Exit 1C feeder road to Harborside Dr. (Highway 275). Turn left onto Harborside Dr. Continue 4.7 miles to Kempner/22nd St. Turn left on Kempner/22nd St., and follow to the cruise terminals.
Note: If you are using a GPS, the following inputs will work best -- to the cruise terminals, 22nd St. and Harborside Dr.; to the parking lots, 33rd St. and Harborside Dr. Also, allow ample time to navigate to the terminals, due to ongoing construction on Interstate 45 between Houston and Galveston.