This was our 9th Regent cruise, our 3rd on Voyager. It tends to be our favourite ship, although we have not cruised on Mariner. (The Paul Gauguin doesn't count; it's in a league of its own, and no longer part of the Regent family.)
We chose this route for the time of year, the embarkation port (Rio), and the value--since this was kind of a "vertical crossing", we thought it would be a good way of testing our tolerance of sea days--we'd previously had two in a row on the Paul Gauguin, but here there were 7 scheduled sea days, with the longest stretch being 3 in a row. This turned out to be plenty for us, not sure we would do a crossing, at least not for another decade.
After a fantastic pre-cruise stay in Rio, we boarded the ship and peeked immediately into our splurge Penthouse B suite. Again, this was an excellent value on this itinerary and it was very worthwhile, although I would not do this on most itineraries where the additional cost over a standard suite is considerable. But the PH is lovely--not a lot bigger than standard, but laid out wonderfully well, with an extra window, and squareish rather than long. We also loved having a butler; this was a real treat for us. Our room was spotless and maintained very nicely throughout with good service from both butler and stewardess.
The PHB cabin we had was the first one forward of the atrium on deck 7. It was a great location, and had no downside. The cabin was in good shape, and the walk-in closet is great. The balcony was above one of the smaller lifeboats, so there was some crew activity out there at times, but it was not bothersome.