Your Ultimate Cruise Guide

MSC Cruises to South America

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Showing results 3136 of 36 cruises
The best cabins sell out fast. See prices now!
390 reviews
51% loved it
  • Large international passenger mix
  • Elegant decor that evokes a boutique hotel
  • Stellar entertainment, from acrobats to singers
Call our partner agents at 866-501-1694 to book your cruise.
9 Night South America Cruise
Buenos Aires Punta del Este Ilhabela Rio de Janeiro Cabo Frio Ilha Grande Buenos Aires
Select a departure date:
2018
JAN
23
TUE
FEB
18
SUN
FEB
27
TUE
MAR
08
THU
MAR
17
SAT
More
Call our partner agents at 866-501-1694 to book your cruise.

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